There is new hope for those of us who suffer from Insomnia. Neurim Pharmaceuticals has developed a new drug, Circadin, which works with the body's natural processes gradually releasing melatonin to induce sleep and restore the sleep cycle.
Traditional sleeping pills have many side effects. Now an Israeli company is introducing a new drug that works with the body's natural processes to induce restful, restorative sleep.Once again researchers in the 100th smallest nation in the world have developed another drug to benefit us all.
When that good night's sleep becomes elusive, sometimes the only option is medication. But the sleeping pills now on the market often come with risks that may outweigh the benefits, inducing dependency, withdrawal symptoms, and occasionally even cognitive impairments such as short-term amnesia.
Not so with Circadin, a new drug produced by Neurim Pharmaceuticals and based on the research of company founder and chief scientific officer Professor Nava Zisapel at Tel Aviv University (TAU).
Unlike other sleep medications which suppress brain activity, Neurim says that Circadin works with the body's natural processes to induce a restful, restorative sleep. It does so by gradually releasing melatonin in the body - the hormone that prepares the body for sleep.
Possibly the worst aspect of insomnia is its deleterious effect on daytime functioning. That's where Circadin has an additional edge over its competitors.
"Circadin not only improves the onset of sleep, but also the quality of sleep," Zisapel, a neuroscientist, tells ISRAEL21c. "People who take the drug have reported that they have better daytime functioning and an improved quality of life."
The drug is already being distributed in Israel and some countries in Europe by Neurim, which was set up in 1991 by Zisapel and her husband, entrepreneur Yehuda Zisapel (founder of the RAD Group), to develop treatments for age-related disorders. It is now in the process of obtaining approval from the US Food and Drug Administration (FDA).
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